1. VMAP
  2. Data
  3. Data Dictionary
  4. Fluid Biomarkers
record_info Demographics Medical History
APOE Genotype
Cognitive Complaint Module Neuropsychological Assessment
Cerebrospinal Fluid (CSF) Research Biomarkers Blood-based Research Biomarkers
Cardiac Structure and Function -- Echocardiogram Cardiac Structure and Function -- MRI Cardiac Strain -- MRI
Brain MRI: White Matter Hyperintensities (FLAIR) Brain MRI: Grey Matter Volume (T1) Diffusion Tensor Imaging Brain MRI: Cerebral Blood Flow (CBF) ROI -- PCASL Brain MRI: Cerebral Small Vessel Disease Markers

Fluid Biomarkers

Cerebrospinal Fluid (CSF) Research Biomarkers

Variable Label
csf_msdabtriplex_abx42_2014 CSF Abeta42 (MSD Abeta Triplex, 2014)
csf_msdabtriplex_abx40_2014 CSF Abeta40 (MSD Abeta Triplex, 2014)
csf_msdabtriplex_abx42_abx40_ratio CSF Abeta42/Abeta40 Ratio (MSD Abeta Triplex, 2014)
csf_innotest_ab1_42_2014 CSF Abeta 1-42 (Fujirebio INNOTEST ELISA, 2014)
csf_innotest_tau_2014 CSF Total tau (Fujirebio INNOTEST ELISA, 2014)
csf_innotest_ptau_2014 CSF p-tau (Fujirebio INNOTEST ELISA, 2014)
csf_umandiagnostics_nfl_2016 CSF Neurofilament Light (UmanDiagnostics, 2016)
csf_elisang36_neurogranin_2016 CSF Neurogranin (ELISA Ng36, 2016)
csf_rdsystemselisa_ykl40_2016 CSF YKL-40 (R&D System ELISA, 2016)
csf_fujirebionm4elisa_gap43_2018 CSF GAP-43 (Fujirebio ELISA NM4, 2018)
csf_beckmancoulter_immage_albumin_2018 CSF Albumin (Beckman Coulter IMMAGE, 2018)
csf_beckmancoulter_immage_plasma_albumin_ratio_2018 CSF/Plasma Albumin Ratio (Beckman Coulter IMMAGE, 2018)
csf_msdassay_strem2_2018 CSF sTREM2 (MSD Assay, 2018)
csf_rdsystems_brevican_2019 CSF Brevican (R&D System, 2019)
csf_rdsystems_timp1_2019 CSF TIMP1 (R&D System, 2019)
csf_rdsystems_timp2_2019 CSF TIMP2 (R&D System, 2019)
csf_rdsystems_mmp2_2019 CSF MMP2 (R&D System, 2019)
csf_mesoscalediscoverymmp3plex_mmp3_2019 CSF MMP3 (Meso Scale Discovery Multiplex Assay, 2019)
csf_mesoscalediscoverymmp3plex_mmp9_2019 CSF MMP9 (Meso Scale Discovery Multiplex Assay, 2019)
csf_fujirebio_ab40_2022 CSF Abeta40 (Fujirebio Lumipulse, 2022)
csf_fujirebio_ab42_2022 CSF Abeta42 (Fujirebio Lumipulse, 2022)
csf_fujirebio_tau_2022 CSF Total tau (Fujirebio Lumipulse, 2022)
csf_fujirebio_ptau_2022 CSF p-tau (Fujirebio Lumipulse, 2022)
csf_rdsystemselisa_ykl40_2022 CSF YKL-40 (R&D System ELISA, 2022)
csf_mesoscalediscoveryecl_strem2_2022 CSF sTREM2 (Meso Scale Discovery ECL, 2022)
csf_thermofisherelisa_pdgfrb_2022 CSF PDGFR Beta (Thermo Fisher ELISA, 2022)
csf_cobas_albumin_2022 CSF Albumin (ROCHE COBAS, 2022)
csf_elisa_nfl21nfl223_2022 CSF Neurofilament Light (ELISA NfL21 NfL23, 2022)
csf_elisang36_neurogranin_2022 CSF Neurogranin (ELISA Ng36, 2022)
csf_mesoscalediscoveryecl_timp1_2022 CSF TIMP1 (Meso Scale Discovery ECL, 2022)
csf_mesoscalediscoveryecl_timp2_2022 CSF TIMP2 (Meso Scale Discovery ECL, 2022)
csf_mesoscalediscoverymmp3plex_mmp2_2022 CSF MMP2 (Meso Scale Discovery Multiplex Assay, 2022)
csf_mesoscalediscoverymmp3plex_mmp3_2022 CSF MMP3 (Meso Scale Discovery Multiplex Assay, 2022)
csf_mesoscalediscoverymmp3plex_mmp9_2022 CSF MMP9 (Meso Scale Discovery Multiplex Assay, 2022)
csf_mesoscalediscovery_flt1_2022 CSF Flt1 (Meso Scale Discovery, 2022)
csf_raybiotech_elisa_brevican_2022 CSF Brevican (RayBiotech ELISA, 2022)
csf_upenn_innobiaalzbio3_ab1_42_2015 CSF Abeta 1-42 (INNO-BIA AlzBio3, 2015)
csf_upenn_innobiaalzbio3_tau_2015 CSF Total tau (INNO-BIA AlzBio3, 2015)
csf_upenn_innobiaalzbio3_ptau_2015 CSF p-tau (INNO-BIA AlzBio3, 2015)
csf_upenn_innobiaalzbio3_tau_ab1_42_ratio_2015 CSF Total tau/Abeta 1-42 Ratio (INNO-BIA AlzBio3, 2015)
csf_upenn_innobiaalzbio3_ptau_ab1_42_ratio_2015 CSF p-tau/Abeta 1-42 Ratio (INNO-BIA AlzBio3, 2015)
csf_lumipulse_snap_2022_factor CSF SNAP (Fujirebio Lumipulse, 2022)
csf_lumipulse_ab42_40_2022_ratio_positive_factor CSF Abeta42/Abeta40 Ratio Positive (Fujirebio Lumipulse, 2022)
csf_lumipulse_ab42_40_2022_ratio CSF Abeta42/Abeta40 Ratio (Fujirebio Lumipulse, 2022)
csf_lumipulse_ptau_2022_positive_factor CSF p-tau Positive (Fujirebio Lumipulse, 2022)
csf_lumipulse_tau_2022_positive_factor CSF Total tau Positive (Fujirebio Lumipulse, 2022)
csf_lumipulse_ab42_2022_positive_factor CSF Abeta42 Positive (Fujirebio Lumipulse, 2022)
csf_innotest_snap_2014_factor CSF SNAP (Fujirebio INNOTEST ELISA, 2014)
csf_msdabtriplex_abx42_40_2014_ratio CSF Abeta42/Abeta40 Ratio (Triplex MSD-measurements, 2014)
csf_innotest_ptau_2014_positive_factor CSF p-tau Positive (Fujirebio INNOTEST ELISA, 2014)
csf_innotest_tau_2014_positive_factor CSF Total tau Positive (Fujirebio INNOTEST ELISA, 2014)
csf_innotest_ab1_42_2014_positive_factor CSF Abeta 1-42 Positive (Fujirebio INNOTEST ELISA, 2014)

Blood-based Research Biomarkers

Variable Label
biomarkers_milliplex_leptin_plasma_2015 Plasma Leptin (MILLIPLEX, 2015)
biomarkers_milliplex_il6_plasma_2015 Plasma IL-6 (MILLIPLEX, 2015)
biomarkers_milliplex_tnfalpha_plasma_2015 Plasma TNFalpha (MILLIPLEX, 2015)
biomarkers_milliplex_vegf_plasma_2015 Plasma VEGF (MILLIPLEX, 2015)
biomarkers_milliplex_vegf_serum_2016 Serum VEGF (MILLIPLEX, 2015)
biomarkers_simoa_umandiagnostics_nfl_plasma_2018 Plasma Neurofilament Light (UmanDiagnostics Simoa, 2018)
biomarkers_quanterix_tau_plasma_2018 Plasma Tau (Quanterix, 2018)
biomarkers_innotest_ab1_42_plasma_2018 Plasma Abeta 1-42 (Fujirebio INNOTEST ELISA, 2018)
biomarkers_msdabetatriplex_abx40_plasma_2018 Plasma Abeta X-40 (MSD Abeta Triplex, 2018)
biomarkers_beckmancoulter_immage_albumin_plasma_2019 Plasma Albumin (Beckman Coulter IMMAGE, 2019)
biomarkers_quanterixsimoa_ab40_plasma_2022 Plasma Abeta40 (Quanterix Simoa, 2022)
biomarkers_quanterixsimoa_ab42_plasma_2022 Plasma Abeta42 (Quanterix Simoa, 2022)
biomarkers_quanterixsimoa_nfl_plasma_2022 Plasma Neurofilament Light (Quanterix Simoa, 2022)
biomarkers_cobas_albumin_plasma_2022 Plasma Albumin (ROCHE COBAS, 2022)
biomarkers_thermofisherelisa_pdgfrb_plasma_2022 Plasma PDGFR Beta (Thermo Fisher ELISA, 2022)
biomarkers_quanterixsimoa_gfap_plasma_2022 Plasma GFAP (Quanterix Simoa, 2022)
biomarkers_quanterixsimoa_ptau231_plasma_2022 Plasma p-tau 231 (Quanterix Simoa, 2022)
biomarkers_mesoscalediscovery_flt1_plasma_2022 Plasma Flt1 (Meso Scale Discovery, 2022)